| Experiment |
P-value |
Statistical test |
Experimental factor |
Summary |
Blood meal time series (Marinotti et al., 2005)
experiment info plots and data
Data from one reporter: Ag.2L.10.0_CDS_at
|
0.0 |
ANOVA |
| Growth condition |
 |
|
Significant differential expression
↑ Blood-fed 24h
↓ Blood-fed 72h |
|
8.8e-08 |
Neighbour t-test |
| Growth condition |
|
|
Significant upward change in expression between:
← Blood-fed 3h
→ Blood-fed 24h |
|
5.2e-06 |
Neighbour t-test |
| Growth condition |
|
|
Significant downward change in expression between:
← Blood-fed 24h
→ Blood-fed 48h |
|
0.0040 |
Neighbour t-test |
| Growth condition |
|
|
Significant downward change in expression between:
← Blood-fed 48h
→ Blood-fed 72h |
|
0.042 |
Neighbour t-test |
| Growth condition |
|
|
Significant upward change in expression between:
← Blood-fed 96h
→ Blood-fed 15d |
|
0.069 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant upward change in expression between:
← Blood-fed 72h
→ Blood-fed 96h |
|
0.10 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant upward change in expression between:
← Non-blood-fed
→ Blood-fed 3h |
 |
Two consecutive blood meals (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.10.0_CDS_at
|
6.9e-10 |
ANOVA |
| Growth condition |
|
|
Significant differential expression
↑ Blood-fed 24h
↓ Non-blood-fed |
|
0.00014 |
Neighbour t-test |
| Growth condition |
|
|
Significant upward change in expression between:
← Non-blood-fed
→ Blood-fed 24h |
|
0.011 |
Neighbour t-test |
| Growth condition |
|
|
Significant downward change in expression between:
← Blood-fed 24h
→ Blood-fed twice |
|
Larval and adult stages (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.10.0_CDS_at
|
1.3e-05 |
ANOVA |
| Developmental stage |
 |
|
Significant differential expression
↑ larva
↓ adult |
M and S form gravid females (Cassone et al., 2008)
experiment infoplots and data
Data from one reporter: Ag.2L.10.0_CDS_at
|
0.00027 |
ANOVA |
| Genotype and strain or line |
  |
|
Significant differential expression
↑ M form:M-GA-CAM
↓ S form:Pimperena |
|
0.13 |
ANOVA |
| Genotype |
|
|
Non-significant differential expression
↑ M form
↓ S form |
|
M and S form virgin females (Cassone et al., 2008)
experiment infoplots and data
Data from one reporter: Ag.2L.10.0_CDS_at
|
0.00038 |
ANOVA |
| Genotype and strain or line |
|
|
Significant differential expression
↑ M form:M-GA-CAM
↓ M form:Mali-NIH |
|
0.93 |
ANOVA |
| Genotype |
|
|
Non-significant differential expression
↑ S form
↓ M form |
|
Plasmodium berghei midgut invasion stage comparisons (Vlachou et al., 2005)
experiment infoplots and data
Data from one reporter: NAP1-P157-D-06
|
0.00064 |
t-test |
| Disease state and disease staging |
  |
|
Significant 5.4-fold down-regulation with respect to
invasion-deficient parasite infection:after midgut invasion v during midgut invasion |
|
0.016 |
t-test |
| Disease state and disease staging |
|
|
Significant 1.4-fold up-regulation with respect to
invasion-deficient parasite infection:during midgut invasion v before midgut invasion |
|
0.021 |
t-test |
| Disease state and disease staging |
|
|
Significant 4.0-fold down-regulation with respect to
wild-type parasite infection:after midgut invasion v during midgut invasion |
|
0.82 |
t-test |
| Disease state and disease staging |
|
|
Non-significant 1.0-fold down-regulation with respect to
wild-type parasite infection:during midgut invasion v before midgut invasion |
|
Blood-fed adult female tissues (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.10.0_CDS_at
|
0.00091 |
ANOVA |
| Organism part |
 |
|
Significant differential expression
↑ midgut [TGMA:0001036]
↓ ovaries |
Plasmodium berghei midgut invasion time-series (Vlachou et al., 2005)
experiment infoplots and data
Data from one reporter: NAP1-P157-D-06
|
0.0018 |
t-test |
| Disease state and disease staging |
|
|
Significant 2.0-fold down-regulation with respect to
wild-type parasite infection v invasion-deficient parasite infection:during midgut invasion |
|
0.28 |
t-test |
| Disease state and disease staging |
|
|
Non-significant 1.4-fold down-regulation with respect to
wild-type parasite infection v invasion-deficient parasite infection:after midgut invasion |
|
0.69 |
t-test |
| Disease state and disease staging |
|
|
Non-significant 1.0-fold up-regulation with respect to
wild-type parasite infection v invasion-deficient parasite infection:before midgut invasion |
|
Developmental series (Koutsos et al., 2007)
experiment infoplots and data
Data from one reporter: NAP1-P157-D-06
|
0.0060 |
ANOVA |
| Developmental stage and age |
 |
|
Significant differential expression
↑ pupa:240 hours
↓ embryo:12-14 hours |
|
0.021 |
Neighbour t-test |
| Developmental stage and age |
|
|
Significant downward change in expression between:
← pupa:240 hours
→ adult:312 hours |
|
0.070 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant upward change in expression between:
← embryo:12-14 hours
→ larva:48 hours |
|
0.098 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant upward change in expression between:
← larva:240 hours
→ pupa:240 hours |
|
0.11 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant upward change in expression between:
← larva:96 hours
→ larva:144 hours |
|
0.12 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant downward change in expression between:
← larva:48 hours
→ larva:96 hours |
|
0.26 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant downward change in expression between:
← larva:144 hours
→ larva:192 hours |
|
0.38 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant upward change in expression between:
← larva:192 hours
→ larva:240 hours |
|
Blood meal after 15 days (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.10.0_CDS_at
|
0.0084 |
ANOVA |
| Growth condition |
|
|
Significant differential expression
↑ Non-blood-fed 18d
↓ Blood-fed 15d |
Alimentary canal compartments (Neira Oviedo et al., 2008)
experiment infoplots and data
Data from one reporter: Ag.2L.10.0_CDS_at
|
0.0089 |
ANOVA |
| Organism part |
|
|
Significant differential expression
↑ gastric caeca [TGMA:0001686]
↓ hindgut [TGMA:0001612] |
Embryonic serosa (Goltsev et al., 2009)
experiment infoplots and data
Data from one reporter: Ag.2L.10.0_CDS_at
|
0.072 |
ANOVA |
| Organism part |
|
|
Non-significant differential expression
↑ embryonic serosa
↓ embryo |
Embryonic development (Goltsev et al., 2009)
experiment infoplots and data
Data from one reporter: Ag.2L.10.0_CDS_at
|
0.11 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 34h
→ 37h |
|
0.19 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 28.5h
→ 31h |
|
0.22 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 37h
→ 40h |
|
0.32 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 43h
→ 46h |
|
0.34 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 6h
→ 7h |
|
0.37 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 22h
→ 25h |
|
0.44 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 25h
→ 28.5h |
|
0.54 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 10h
→ 13h |
|
0.59 |
ANOVA |
| Age |
|
|
Non-significant differential expression
↑ 31h
↓ 37h |
|
0.59 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 16h
→ 19h |
|
0.81 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 19h
→ 22h |
|
0.84 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 8h
→ 10h |
|
0.86 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 31h
→ 34h |
|
0.91 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 13h
→ 16h |
|
0.92 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 7h
→ 8h |
|
0.98 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 2h
→ 4h |
|
0.99 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 4h
→ 6h |
|
0.99 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 40h
→ 43h |
|
Larval salivary glands (Neira Oviedo et al., 2009)
experiment infoplots and data
Data from one reporter: Ag.2L.10.0_CDS_at
|
0.13 |
ANOVA |
| Organism part |
|
|
Non-significant differential expression
↑ salivary gland [TGMA:0001812]
↓ whole_organism |
Chloroquine exposure (Abrantes et al., 2008)
experiment infoplots and data
Data from one reporter: NAP1-P157-D-06
|
0.19 |
t-test |
| Compound and disease state |
 |
|
Non-significant 2.2-fold down-regulation with respect to
chloroquine v none:uninfected |
|
0.95 |
t-test |
| Compound and disease state |
|
|
Non-significant 1.0-fold up-regulation with respect to
chloroquine v none:Plasmodium berghei infected |
|
Mated females (Rogers et al., 2009)
experiment infoplots and data
Data from one reporter: Ag.2L.10.0_CDS_at
|
0.23 |
ANOVA |
| Growth condition |
|
|
Non-significant differential expression
↑ mated 6h
↓ virgin 0h |
|
0.26 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant downward change in expression between:
← mated 6h
→ mated 24h |
|
0.27 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant upward change in expression between:
← virgin 0h
→ mated 2h |
|
0.41 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant upward change in expression between:
← mated 2h
→ mated 6h |
|
Adult female tissues (Koutsos et al., 2007)
experiment infoplots and data
Data from one reporter: NAP1-P157-D-06
|
0.30 |
ANOVA |
| Organism part |
|
|
Non-significant differential expression
↑ carcass
↓ ovaries |
M and S form 4th instar larvae (Cassone et al., 2008)
experiment infoplots and data
Data from one reporter: Ag.2L.10.0_CDS_at
|
0.37 |
ANOVA |
| Genotype |
|
|
Non-significant differential expression
↑ M form
↓ S form |
|
0.54 |
ANOVA |
| Genotype and strain or line |
|
|
Non-significant differential expression
↑ M form:Mali-NIH
↓ S form:KIST |
|
Male vs. female (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.10.0_CDS_at
|
0.52 |
ANOVA |
| Sex |
 |
|
Non-significant differential expression
↑ female
↓ male |
Male vs. female (Koutsos et al., 2007)
experiment infoplots and data
Data from one reporter: NAP1-P157-D-06
|
0.55 |
ANOVA |
| Sex |
|
|
Non-significant differential expression
↑ female
↓ male |
