| Experiment |
P-value |
Statistical test |
Experimental factor |
Summary |
Blood meal time series (Marinotti et al., 2005)
experiment info plots and data
Data from one reporter: Ag.2L.1000.0_CDS_at
|
6.8e-14 |
ANOVA |
| Growth condition |
 |
|
Significant differential expression
↑ Blood-fed 3h
↓ Blood-fed 48h |
|
0.00010 |
Neighbour t-test |
| Growth condition |
|
|
Significant downward change in expression between:
← Blood-fed 3h
→ Blood-fed 24h |
|
0.00012 |
Neighbour t-test |
| Growth condition |
|
|
Significant upward change in expression between:
← Non-blood-fed
→ Blood-fed 3h |
|
0.057 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant downward change in expression between:
← Blood-fed 24h
→ Blood-fed 48h |
|
0.057 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant upward change in expression between:
← Blood-fed 72h
→ Blood-fed 96h |
|
0.19 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant downward change in expression between:
← Blood-fed 96h
→ Blood-fed 15d |
|
0.48 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant upward change in expression between:
← Blood-fed 48h
→ Blood-fed 72h |
 |
Embryonic development (Goltsev et al., 2009)
experiment infoplots and data
Data from one reporter: Ag.2L.1000.0_CDS_at
|
8.8e-13 |
ANOVA |
| Age |
 |
|
Significant differential expression
↑ 43h
↓ 2h |
|
0.038 |
Neighbour t-test |
| Age |
|
|
Significant downward change in expression between:
← 31h
→ 34h |
|
0.097 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 2h
→ 4h |
|
0.12 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 19h
→ 22h |
|
0.22 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 34h
→ 37h |
|
0.22 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 43h
→ 46h |
|
0.27 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 40h
→ 43h |
|
0.30 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 28.5h
→ 31h |
|
0.31 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 37h
→ 40h |
|
0.52 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 7h
→ 8h |
|
0.60 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 6h
→ 7h |
|
0.62 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 8h
→ 10h |
|
0.70 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 16h
→ 19h |
|
0.73 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 4h
→ 6h |
|
0.75 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 13h
→ 16h |
|
0.76 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 22h
→ 25h |
|
0.79 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 10h
→ 13h |
|
0.85 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 25h
→ 28.5h |
|
Developmental series (Koutsos et al., 2007)
experiment infoplots and data
Data averaged over multiple reporters. show details
|
1.2e-11 |
ANOVA |
| Developmental stage and age |
 |
|
Significant differential expression
↑ larva:96 hours
↓ embryo:12-14 hours |
|
0.00011 |
Neighbour t-test |
| Developmental stage and age |
|
|
Significant upward change in expression between:
← embryo:12-14 hours
→ larva:48 hours |
|
0.017 |
Neighbour t-test |
| Developmental stage and age |
|
|
Significant downward change in expression between:
← larva:144 hours
→ larva:192 hours |
|
0.10 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant downward change in expression between:
← pupa:240 hours
→ adult:312 hours |
|
0.32 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant downward change in expression between:
← larva:96 hours
→ larva:144 hours |
|
0.34 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant downward change in expression between:
← larva:192 hours
→ larva:240 hours |
|
0.66 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant upward change in expression between:
← larva:48 hours
→ larva:96 hours |
|
0.67 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant upward change in expression between:
← larva:240 hours
→ pupa:240 hours |
|
Alimentary canal compartments (Neira Oviedo et al., 2008)
experiment infoplots and data
Data from one reporter: Ag.2L.1000.0_CDS_at
|
0.00024 |
ANOVA |
| Organism part |
 |
|
Significant differential expression
↑ hindgut [TGMA:0001612]
↓ posterior midgut [TGMA:0001802] |
Male vs. female (Koutsos et al., 2007)
experiment infoplots and data
Data averaged over multiple reporters. show details
|
0.010 |
ANOVA |
| Sex |
 |
|
Significant differential expression
↑ male
↓ female |
Two consecutive blood meals (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.1000.0_CDS_at
|
0.018 |
ANOVA |
| Growth condition |
|
|
Significant differential expression
↑ Non-blood-fed
↓ Blood-fed twice |
|
0.043 |
Neighbour t-test |
| Growth condition |
|
|
Significant downward change in expression between:
← Blood-fed 24h
→ Blood-fed twice |
|
0.18 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant downward change in expression between:
← Non-blood-fed
→ Blood-fed 24h |
|
Blood-fed adult female tissues (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.1000.0_CDS_at
|
0.023 |
ANOVA |
| Organism part |
|
|
Significant differential expression
↑ midgut [TGMA:0001036]
↓ ovaries |
Larval salivary glands (Neira Oviedo et al., 2009)
experiment infoplots and data
Data from one reporter: Ag.2L.1000.0_CDS_at
|
0.039 |
ANOVA |
| Organism part |
|
|
Significant differential expression
↑ whole_organism
↓ salivary gland [TGMA:0001812] |
M and S form virgin females (Cassone et al., 2008)
experiment infoplots and data
Data from one reporter: Ag.2L.1000.0_CDS_at
|
0.076 |
ANOVA |
| Genotype and strain or line |
  |
|
Non-significant differential expression
↑ S form:Pimperena
↓ M form:M-GA-CAM |
|
0.12 |
ANOVA |
| Genotype |
|
|
Non-significant differential expression
↑ S form
↓ M form |
|
M and S form gravid females (Cassone et al., 2008)
experiment infoplots and data
Data from one reporter: Ag.2L.1000.0_CDS_at
|
0.079 |
ANOVA |
| Genotype and strain or line |
|
|
Non-significant differential expression
↑ S form:Pimperena
↓ M form:Mali-NIH |
|
0.11 |
ANOVA |
| Genotype |
|
|
Non-significant differential expression
↑ S form
↓ M form |
|
Plasmodium berghei midgut invasion stage comparisons (Vlachou et al., 2005)
experiment infoplots and data
Data averaged over multiple reporters. show details
|
0.13 |
t-test |
| Disease state and disease staging |
  |
|
Non-significant 1.2-fold down-regulation with respect to
invasion-deficient parasite infection:after midgut invasion v during midgut invasion |
|
0.34 |
t-test |
| Disease state and disease staging |
|
|
Non-significant 1.1-fold down-regulation with respect to
wild-type parasite infection:after midgut invasion v during midgut invasion |
|
0.41 |
t-test |
| Disease state and disease staging |
|
|
Non-significant 1.1-fold down-regulation with respect to
wild-type parasite infection:during midgut invasion v before midgut invasion |
|
1.0 |
t-test |
| Disease state and disease staging |
|
|
Non-significant fold change (not enough data to calculate) with respect to
invasion-deficient parasite infection:during midgut invasion v before midgut invasion |
|
Mated females (Rogers et al., 2009)
experiment infoplots and data
Data from one reporter: Ag.2L.1000.0_CDS_at
|
0.13 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant downward change in expression between:
← mated 2h
→ mated 6h |
|
0.18 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant upward change in expression between:
← mated 6h
→ mated 24h |
|
0.24 |
ANOVA |
| Growth condition |
|
|
Non-significant differential expression
↑ mated 2h
↓ mated 6h |
|
0.34 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant upward change in expression between:
← virgin 0h
→ mated 2h |
|
Plasmodium berghei midgut invasion time-series (Vlachou et al., 2005)
experiment infoplots and data
Data averaged over multiple reporters. show details
|
0.15 |
t-test |
| Disease state and disease staging |
|
|
Non-significant 1.2-fold down-regulation with respect to
wild-type parasite infection v invasion-deficient parasite infection:during midgut invasion |
|
0.46 |
t-test |
| Disease state and disease staging |
|
|
Non-significant 1.7-fold up-regulation with respect to
wild-type parasite infection v invasion-deficient parasite infection:before midgut invasion |
|
0.64 |
t-test |
| Disease state and disease staging |
|
|
Non-significant 1.1-fold down-regulation with respect to
wild-type parasite infection v invasion-deficient parasite infection:after midgut invasion |
|
Male vs. female (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.1000.0_CDS_at
|
0.16 |
ANOVA |
| Sex |
|
|
Non-significant differential expression
↑ male
↓ female |
Blood meal after 15 days (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.1000.0_CDS_at
|
0.17 |
ANOVA |
| Growth condition |
|
|
Non-significant differential expression
↑ Non-blood-fed 18d
↓ Blood-fed 15d |
Chloroquine exposure (Abrantes et al., 2008)
experiment infoplots and data
Data averaged over multiple reporters. show details
|
0.33 |
t-test |
| Compound and disease state |
 |
|
Non-significant 1.1-fold up-regulation with respect to
chloroquine v none:Plasmodium berghei infected |
|
0.97 |
t-test |
| Compound and disease state |
|
|
Non-significant 1.0-fold down-regulation with respect to
chloroquine v none:uninfected |
|
M and S form 4th instar larvae (Cassone et al., 2008)
experiment infoplots and data
Data from one reporter: Ag.2L.1000.0_CDS_at
|
0.35 |
ANOVA |
| Genotype and strain or line |
|
|
Non-significant differential expression
↑ M form:Mali-NIH
↓ M form:M-GA-CAM |
|
0.60 |
ANOVA |
| Genotype |
|
|
Non-significant differential expression
↑ S form
↓ M form |
|
Adult female tissues (Koutsos et al., 2007)
experiment infoplots and data
Data averaged over multiple reporters. show details
|
0.37 |
ANOVA |
| Organism part |
|
|
Non-significant differential expression
↑ head [TGMA:0000002]
↓ midgut [TGMA:0001036] |
Embryonic serosa (Goltsev et al., 2009)
experiment infoplots and data
Data from one reporter: Ag.2L.1000.0_CDS_at
|
0.79 |
ANOVA |
| Organism part |
|
|
Non-significant differential expression
↑ embryonic serosa
↓ embryo |
Larval and adult stages (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.1000.0_CDS_at
|
0.97 |
ANOVA |
| Developmental stage |
|
|
Non-significant differential expression
↑ adult
↓ larva |
