| Experiment |
P-value |
Statistical test |
Experimental factor |
Summary |
Embryonic development (Goltsev et al., 2009)
experiment info plots and data
Data from one reporter: Ag.2L.1011.0_CDS_at
|
1.3e-10 |
ANOVA |
| Age |
 |
|
Significant differential expression
↑ 2h
↓ 13h |
|
0.016 |
Neighbour t-test |
| Age |
|
|
Significant downward change in expression between:
← 2h
→ 4h |
|
0.076 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 4h
→ 6h |
|
0.11 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 13h
→ 16h |
|
0.23 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 37h
→ 40h |
|
0.29 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 6h
→ 7h |
|
0.35 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 8h
→ 10h |
|
0.38 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 10h
→ 13h |
|
0.62 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 16h
→ 19h |
|
0.65 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 43h
→ 46h |
|
0.66 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 34h
→ 37h |
|
0.79 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 28.5h
→ 31h |
|
0.82 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 40h
→ 43h |
|
0.88 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 31h
→ 34h |
|
0.92 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 22h
→ 25h |
|
0.94 |
Neighbour t-test |
| Age |
|
|
Non-significant upward change in expression between:
← 7h
→ 8h |
|
0.98 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 19h
→ 22h |
|
1.0 |
Neighbour t-test |
| Age |
|
|
Non-significant downward change in expression between:
← 25h
→ 28.5h |
 |
M and S form virgin females (Cassone et al., 2008)
experiment infoplots and data
Data from one reporter: Ag.2L.1011.0_CDS_at
|
9.5e-06 |
ANOVA |
| Genotype and strain or line |
  |
|
Significant differential expression
↑ M form:M-GA-CAM
↓ M form:Mali-NIH |
|
0.61 |
ANOVA |
| Genotype |
|
|
Non-significant differential expression
↑ S form
↓ M form |
|
M and S form gravid females (Cassone et al., 2008)
experiment infoplots and data
Data from one reporter: Ag.2L.1011.0_CDS_at
|
2.4e-05 |
ANOVA |
| Genotype and strain or line |
|
|
Significant differential expression
↑ S form:KIST
↓ S form:Pimperena |
|
0.85 |
ANOVA |
| Genotype |
|
|
Non-significant differential expression
↑ M form
↓ S form |
|
Blood meal time series (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.1011.0_CDS_at
|
2.8e-05 |
ANOVA |
| Growth condition |
 |
|
Significant differential expression
↑ Blood-fed 72h
↓ Blood-fed 3h |
|
0.0044 |
Neighbour t-test |
| Growth condition |
|
|
Significant downward change in expression between:
← Blood-fed 72h
→ Blood-fed 96h |
|
0.024 |
Neighbour t-test |
| Growth condition |
|
|
Significant upward change in expression between:
← Blood-fed 24h
→ Blood-fed 48h |
|
0.16 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant upward change in expression between:
← Blood-fed 3h
→ Blood-fed 24h |
|
0.21 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant downward change in expression between:
← Non-blood-fed
→ Blood-fed 3h |
|
0.60 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant upward change in expression between:
← Blood-fed 48h
→ Blood-fed 72h |
|
0.91 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant downward change in expression between:
← Blood-fed 96h
→ Blood-fed 15d |
|
Plasmodium berghei midgut invasion stage comparisons (Vlachou et al., 2005)
experiment infoplots and data
Data from one reporter: 4A3B-AAW-E-10
|
0.00035 |
t-test |
| Disease state and disease staging |
  |
|
Significant 1.4-fold up-regulation with respect to
wild-type parasite infection:after midgut invasion v during midgut invasion |
|
0.00061 |
t-test |
| Disease state and disease staging |
|
|
Significant 1.6-fold up-regulation with respect to
invasion-deficient parasite infection:after midgut invasion v during midgut invasion |
|
0.016 |
t-test |
| Disease state and disease staging |
|
|
Significant 1.2-fold down-regulation with respect to
invasion-deficient parasite infection:during midgut invasion v before midgut invasion |
|
0.33 |
t-test |
| Disease state and disease staging |
|
|
Non-significant 1.1-fold up-regulation with respect to
wild-type parasite infection:during midgut invasion v before midgut invasion |
|
Mated females (Rogers et al., 2009)
experiment infoplots and data
Data from one reporter: Ag.2L.1011.0_CDS_at
|
0.0013 |
Neighbour t-test |
| Growth condition |
|
|
Significant upward change in expression between:
← mated 2h
→ mated 6h |
|
0.020 |
ANOVA |
| Growth condition |
|
|
Significant differential expression
↑ mated 6h
↓ mated 2h |
|
0.17 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant downward change in expression between:
← mated 6h
→ mated 24h |
|
0.41 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant downward change in expression between:
← virgin 0h
→ mated 2h |
|
Blood-fed adult female tissues (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.1011.0_CDS_at
|
0.0025 |
ANOVA |
| Organism part |
 |
|
Significant differential expression
↑ ovaries
↓ fat body [TGMA:0001856] |
Developmental series (Koutsos et al., 2007)
experiment infoplots and data
Data from one reporter: 4A3B-AAW-E-10
|
0.0039 |
ANOVA |
| Developmental stage and age |
 |
|
Significant differential expression
↑ larva:240 hours
↓ embryo:12-14 hours |
|
0.0091 |
Neighbour t-test |
| Developmental stage and age |
|
|
Significant upward change in expression between:
← embryo:12-14 hours
→ larva:48 hours |
|
0.077 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant downward change in expression between:
← larva:96 hours
→ larva:144 hours |
|
0.094 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant upward change in expression between:
← larva:144 hours
→ larva:192 hours |
|
0.31 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant downward change in expression between:
← pupa:240 hours
→ adult:312 hours |
|
0.55 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant upward change in expression between:
← larva:192 hours
→ larva:240 hours |
|
0.63 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant downward change in expression between:
← larva:48 hours
→ larva:96 hours |
|
0.96 |
Neighbour t-test |
| Developmental stage and age |
|
|
Non-significant downward change in expression between:
← larva:240 hours
→ pupa:240 hours |
|
Two consecutive blood meals (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.1011.0_CDS_at
|
0.0075 |
ANOVA |
| Growth condition |
|
|
Significant differential expression
↑ Blood-fed twice
↓ Blood-fed 24h |
|
0.027 |
Neighbour t-test |
| Growth condition |
|
|
Significant upward change in expression between:
← Blood-fed 24h
→ Blood-fed twice |
|
0.23 |
Neighbour t-test |
| Growth condition |
|
|
Non-significant downward change in expression between:
← Non-blood-fed
→ Blood-fed 24h |
|
Larval salivary glands (Neira Oviedo et al., 2009)
experiment infoplots and data
Data from one reporter: Ag.2L.1011.0_CDS_at
|
0.0086 |
ANOVA |
| Organism part |
|
|
Significant differential expression
↑ whole_organism
↓ salivary gland [TGMA:0001812] |
M and S form 4th instar larvae (Cassone et al., 2008)
experiment infoplots and data
Data from one reporter: Ag.2L.1011.0_CDS_at
|
0.019 |
ANOVA |
| Genotype and strain or line |
|
|
Significant differential expression
↑ S form:KIST
↓ M form:Mali-NIH |
|
0.43 |
ANOVA |
| Genotype |
|
|
Non-significant differential expression
↑ S form
↓ M form |
|
Plasmodium berghei midgut invasion time-series (Vlachou et al., 2005)
experiment infoplots and data
Data from one reporter: 4A3B-AAW-E-10
|
0.019 |
t-test |
| Disease state and disease staging |
|
|
Significant 1.2-fold up-regulation with respect to
wild-type parasite infection v invasion-deficient parasite infection:during midgut invasion |
|
0.21 |
t-test |
| Disease state and disease staging |
|
|
Non-significant 1.0-fold down-regulation with respect to
wild-type parasite infection v invasion-deficient parasite infection:after midgut invasion |
|
0.59 |
t-test |
| Disease state and disease staging |
|
|
Non-significant 1.0-fold down-regulation with respect to
wild-type parasite infection v invasion-deficient parasite infection:before midgut invasion |
|
Male vs. female (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.1011.0_CDS_at
|
0.021 |
ANOVA |
| Sex |
 |
|
Significant differential expression
↑ female
↓ male |
Larval and adult stages (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.1011.0_CDS_at
|
0.081 |
ANOVA |
| Developmental stage |
|
|
Non-significant differential expression
↑ larva
↓ adult |
Male vs. female (Koutsos et al., 2007)
experiment infoplots and data
Data from one reporter: 4A3B-AAW-E-10
|
0.10 |
ANOVA |
| Sex |
|
|
Non-significant differential expression
↑ female
↓ male |
Blood meal after 15 days (Marinotti et al., 2005)
experiment infoplots and data
Data from one reporter: Ag.2L.1011.0_CDS_at
|
0.14 |
ANOVA |
| Growth condition |
|
|
Non-significant differential expression
↑ Blood-fed 15d
↓ Non-blood-fed 18d |
Alimentary canal compartments (Neira Oviedo et al., 2008)
experiment infoplots and data
Data from one reporter: Ag.2L.1011.0_CDS_at
|
0.20 |
ANOVA |
| Organism part |
|
|
Non-significant differential expression
↑ hindgut [TGMA:0001612]
↓ whole_organism |
Chloroquine exposure (Abrantes et al., 2008)
experiment infoplots and data
Data from one reporter: 4A3B-AAW-E-10
|
0.38 |
t-test |
| Compound and disease state |
 |
|
Non-significant 1.2-fold down-regulation with respect to
chloroquine v none:Plasmodium berghei infected |
|
0.46 |
t-test |
| Compound and disease state |
|
|
Non-significant 1.1-fold down-regulation with respect to
chloroquine v none:uninfected |
|
Adult female tissues (Koutsos et al., 2007)
experiment infoplots and data
Data from one reporter: 4A3B-AAW-E-10
|
0.53 |
ANOVA |
| Organism part |
|
|
Non-significant differential expression
↑ carcass
↓ head [TGMA:0000002] |
Embryonic serosa (Goltsev et al., 2009)
experiment infoplots and data
Data from one reporter: Ag.2L.1011.0_CDS_at
|
0.77 |
ANOVA |
| Organism part |
|
|
Non-significant differential expression
↑ embryonic serosa
↓ embryo |
